Humans have another type of DNA inside our cells

Scientists have identified an entirely new kind of DNA inside humans.

This new DNA, known as the “i-motif,” was suggested in previous research, but had only been identified under artificial conditions in a lab. But research published in Nature Chemistry[1] is the first study to confirm its existence inside living beings.

The i-motif looks like a twisted knot, as opposed to DNA’s well-known double helix structure.

In a double helix strand of DNA, there are four compounds that form “bases” — adenine, thymine, cytosine and guanine. Adenine typically binds with thymine while the cytosine binds with guanine, but this isn’t the case in the i-motif.

“The i-motif is a four-stranded ‘knot’ of DNA,” Marcel Dinger, a co-author on the study, said in a press release.[2] “In the knot structure, C [cytosine] letters on the same strand of DNA bind to each other – so this is very different from a double helix, where ‘letters’ on opposite strands recognize each other and where Cs bind to Gs [guanines].”

To find the i-motifs, the scientists engineered antibodies into tiny probes that would attach themselves only to i-motifs. They added fluorescent dye to the probes so they could track exactly where the i-motifs were.

These antibody probes were then placed in three variations of human cells where scientiests had hoped to identify the i-motifs in the nucleus of each cell.

More research is needed to determine the i-motif’s purpose, but the researchers believe the structures help to switch genes “on or off.”

“It’s exciting to uncover a whole new form of DNA in cells,” said Dinger. “These findings will set the stage for a whole new push to understand what this new DNA shape is really for and whether it will impact on health and disease.”

References

  1. ^ published in Nature Chemistry (www.nature.com)
  2. ^ said in a press release. (www.eurekalert.org)

Source URL: Read More
The public content above was dynamically discovered – by graded relevancy to this site’s keyword domain name. Such discovery was by systematic attempts to filter for “Creative Commons“ re-use licensing and/or by Press Release distributions. “Source URL” states the content’s owner and/or publisher. When possible, this site references the content above to generate its value-add, the dynamic sentimental analysis below, which allows us to research global sentiments across a multitude of topics related to this site’s specific keyword domain name. Additionally, when possible, this site references the content above to provide on-demand (multilingual) translations and/or to power its “Read Article to Me” feature, which reads the content aloud to visitors. Where applicable, this site also auto-generates a “References” section, which appends the content above by listing all mentioned links. Views expressed in the content above are solely those of the author(s). We do not endorse, offer to sell, promote, recommend, or, otherwise, make any statement about the content above. We reference the content above for your “reading” entertainment purposes only. Review “DMCA & Terms”, at the bottom of this site, for terms of your access and use as well as for applicable DMCA take-down request.

Acquire this Domain
You can acquire this site’s domain name! We have nurtured its online marketing value by systematically curating this site by the domain’s relevant keywords. Explore our content network – you can advertise on each or rent vs. buy the domain. Buy@TLDtraders.com | Skype: TLDtraders | +1 (475) BUY-NAME (289 – 6263). Thousands search by this site’s exact keyword domain name! Most are sent here because search engines often love the keyword. This domain can be your 24/7 lead generator! If you own it, you could capture a large amount of online traffic for your niche. Stop wasting money on ads. Instead, buy this domain to gain a long-term marketing asset. If you can’t afford to buy then you can rent the domain.

About Us
We are Internet Investors, Developers, and Franchisers – operating a content network of several thousand sites while federating 100+ eCommerce and SaaS startups. With our proprietary “inverted incubation” model, we leverage a portfolio of $100M in valued domains to impact online trends, traffic, and transactions. We use robotic process automation, machine learning, and other proprietary approaches to power our content network. Contact us to learn how we can help you with your online marketing and/or site maintenance.

Share